oral presentation-FMF congress 2016 Learning curve of open and fetoscopic spina bifida repair – a systematic review & meta-analysis Joyeux, A. C. Engels, F. M. Russo, M.P. Eastwood, T. Van Mieghem, P. de Coppi, F. Van Calenbergh, J. Deprest Conclusion:
L. Joyeux: Article published on February 23, 2016 in Fetal Diagnosis and Therapy
Fetoscopic versus Open Repair for Spina Bifida Aperta: A Systematic Review of Outcomes Luc Joyeux (a, b), Alexander C. Engels (a, b), Francesca M. Russo (a, b), Julio Jimenez (a, e), Tim Van Mieghem (a, c), Paolo De Coppi (a,
fetal sheep model of spina bifida-Feb 2015
Since December 2014, our project entitled “Reducing invasiveness of fetal SB repair – towards novel surgical approach and instrumentation” has obtained approval of the institutional Ethics Committee of our university KU Leuven (number P285-2014). In our Academic Department Development and
fetal sheep model of spina bifida-March 2015
With my colleague Alexander Engels, we have completely reproduced the fetal lamb model of open spina bifida by surgical induction at 75 days of gestation (Meuli-1995). Following a midline laparotomy and 6-7 cm hysterotomy under general anesthesia, this fetal surgery
fetal sheep model of spina bifida-April 2015
With my colleague Alexander Engels, we have exhaustively reproduced the standard postnatal readouts of this fetal lamb model of open spina bifida. Harvest was realized at 143 days (term 145 days): after sedation of the ewe, delivery was performed under
fetal sheep model of spina bifida-May 2015
With my colleague Alexander Engels, we are improving the readouts of the fetal lamb model of open spina bifida: Analysis of watertightness of lesion: just prior to delivery an amniocentesis was performed to test for AcetylCholinesterase and alpha-FetoProtein in the